Which antidote is indicated for iron overdose or toxicity?

• A. Digiband
• B. Deferoxamine
• C. N-acetylcysteine
• D. Flumazenil

Answer: (B)

Deferoxamine is the antidote used for iron overdose or toxicity. This chelating agent specifically binds to free iron in the bloodstream, facilitating its excretion through the kidneys. In cases of iron poisoning, iron accumulates in organs, leading to potential damage. Deferoxamine reduces the free iron levels, helping to mitigate the toxic effects and prevent organ damage.

In comparison, other options are not suitable for treating iron toxicity. For example, Digiband is used in cases of digoxin toxicity, while N-acetylcysteine serves as an antidote for acetaminophen overdose. Flumazenil is an antagonist for benzodiazepine overdose. Each of these antidotes has a specific clinical indication that does not overlap with the treatment of iron toxicity, which further emphasizes the appropriateness of deferoxamine for this condition.