Which adverse effect is commonly associated with tetracyclines?

• A. Nephrotoxicity
• B. Superinfections
• C. Ototoxicity
• D. Sun sensitivity

Answer: (D)

Tetracyclines are known to cause sun sensitivity, or photosensitivity, as a common adverse effect. This sensitivity occurs because tetracyclines can interact with ultraviolet (UV) light, leading to an increased risk of sunburn or skin rashes upon exposure to sunlight. Patients taking these medications are often advised to wear protective clothing and use sunscreen to mitigate this effect. It's essential for healthcare providers to inform patients about this risk so they can take appropriate precautions while on tetracycline therapy.

Nephrotoxicity, superinfections, and ototoxicity are potential adverse effects of various antibiotics, but they are not as closely associated with tetracyclines specifically. While superinfections can occur with many antibiotics due to disruption of normal flora, the hallmark adverse effect associated with tetracyclines is the increased sensitivity to sunlight.