What is the antidote for opioid overdose?

• A. Naloxone
• B. Glucagon
• C. Librium
• D. Atropine

Answer: (A)

Naloxone is the antidote for opioid overdose because it is an opioid antagonist that works by binding to the same receptors in the brain that opioids target. When administered, naloxone effectively displaces opioids from these receptors, reversing the effects of opioid toxicity, including respiratory depression and sedation. This rapid action can restore normal breathing and consciousness in individuals experiencing an opioid overdose.

The other options listed do not serve as antidotes for opioid overdose. Glucagon is mainly used to treat hypoglycemia or beta-blocker overdose, Librium is a brand name for chlordiazepoxide, which is used for anxiety and alcohol withdrawal, and atropine is utilized primarily for bradycardia and certain types of poisoning, but not for opioid overdose. This specific action and effectiveness in reversing the effects of opioid overdose make naloxone the correct choice in this scenario.