What is a common sign of digoxin toxicity?

• A. Headache
• B. Bradycardia
• C. Dry mouth
• D. Hyperactivity

Answer: (B)

Bradycardia is a well-known sign of digoxin toxicity due to the drug's action on the cardiovascular system. Digoxin works by increasing the force of myocardial contraction and slowing down the heart rate by enhancing vagal tone, which can lead to an excessively slow heart rate when toxic levels are present. This bradycardia can manifest as a significantly reduced pulse rate, causing concern in clinical settings.

Other signs of digoxin toxicity may include nausea, vomiting, visual disturbances, and changes in mental status, but bradycardia is particularly notable because it provides a direct indication of the drug's profound effect on heart rhythm. Monitoring pulse rates is essential for patients taking digoxin, especially if they have any additional risk factors for toxicity, such as renal impairment or interactions with other medications.

Recognizing bradycardia as a sign of digoxin toxicity allows healthcare professionals to intervene promptly, adjusting dosages or discontinuing the drug if necessary to avoid potentially severe complications associated with this condition.