What class of drugs includes omeprazole and lansoprazole?

• A. H2 Receptor Antagonists
• B. Proton Pump Inhibitors (PPIs)
• C. Antacids
• D. Beta-blockers

Answer: (B)

Omeprazole and lansoprazole belong to the class of drugs known as Proton Pump Inhibitors (PPIs). These medications work by irreversibly inhibiting the proton pump in the parietal cells of the stomach lining, which is responsible for the final step in the production of gastric acid. By blocking this pump, PPIs significantly reduce the secretion of gastric acid, thereby providing relief from conditions associated with excessive stomach acid, such as gastroesophageal reflux disease (GERD) and peptic ulcers.

PPIs are particularly effective for long-term management of acid-related disorders and often have a longer duration of action compared to other classes of acid-reducing medications. Their ability to promote healing of esophageal and gastric tissue in acid-related diseases makes them a cornerstone in gastrointestinal pharmacotherapy.